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在固体脂质微粒中使用多态态修饰剂:结构修饰对药物释放性能的作用

Serena Bertoni1, Elena Simone2, Stefano Sangiorgi1

  • 1Department of Pharmacy and Biotechnology, University of Bologna, Via S. Donato 19/2, Bologna 40127, Italy.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
|November 23, 2023
PubMed
概括

液体添加剂修改了tristearin固体脂质微粒,加速了多态转变并改变了药物释放动力学. 一些添加剂释放时间延长,而另一些添加剂表现出随着时间的推移稳定的配置,突出了结构与性质的相关性.

关键词:
有控制释放的释放.微球是微球的组成部分.多态性多态性多态性固态硬件是一种固态硬件.喷雾凝结的凝结同步机SAXSS的同步机在悲伤的表情中.

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