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Updated: Jul 10, 2025

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依赖于Nod1的NF-kB激活启动了血液生成干细胞的特异化,以应对小Rho GTPases

Xiaoyi Cheng1, Radwa Barakat1,2, Giulia Pavani3

  • 1Department of Genetics, Development and Cell Biology, Iowa State University, Ames, IA, 50011, USA.

Nature communications
|November 23, 2023
PubMed
概括

在内皮细胞中激活Nod1-Ripk2-NF-kB通路使其为造血干细胞和原生细胞 (HSPC) 发育做好了准备. 这一发现为改进细胞疗法和HSPC移植提供了潜力.

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