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Updated: Jul 10, 2025

Quantitative, Real-time Analysis of Base Excision Repair Activity in Cell Lysates Utilizing Lesion-specific Molecular Beacons
15:01

Quantitative, Real-time Analysis of Base Excision Repair Activity in Cell Lysates Utilizing Lesion-specific Molecular Beacons

Published on: August 6, 2012

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核酸切除修复缺陷是清细胞脏细胞癌中可向的治疗脆弱性

Aurel Prosz1, Haohui Duan2,3, Viktoria Tisza4,5

  • 1Danish Cancer Institute, Copenhagen, Denmark.

Scientific reports
|November 23, 2023
PubMed
概括

清细胞细胞癌 (ccRCC) 可能存在核酸切除修复 (NER) 缺陷,使其对向治疗敏感. 一些患有NER缺乏和高PTGR1表达的ccRCC患者可能对irofulven治疗有反应.

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