评估一种具有延长时间的抗微生物活性的新型表面涂层配方,用于卫生保健环境消毒
Roberto Bruno Maria Marano1, Diana Merezhko1, Keren Anat Resnick1
1Department of Health Policy and Management, School of Public Health, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel.
Antimicrobial resistance and infection control
|November 23, 2023
概括
一种新的消毒剂,OxiLastTM,可在长达七天的时间内显著减少表面上的细菌污染. 这项创新提供了持续的抗菌作用,改善了医院的消毒,减少了医疗保健相关的感染.
科学领域:
- 微生物学 微生物学
- 传染性疾病 传染性疾病
- 环境健康 环境健康
背景情况:
- 环境污染是医院内病原体传播的主要因素.
- 目前的医院表面消毒做法往往不够理想.
- 需要新的消毒策略来减少与医疗相关的感染.
研究的目的:
- 评估OxiLastTM的持续抗菌作用,这是一种新型配方,可以扩大基消毒剂的活性.
- 评估OxiLastTM对表面常见的细菌病原体的疗效.
- 为了确定OxiLastTM在各种条件下的耐用性和强度.
主要方法:
- 实验室实验包括用OxiLastTM涂抹PVC表面,并用Gram-阳性和Gram-阴性细菌接种.
- 在不同的接触时间 (5,15,30分钟) 测量了细菌减少.
- 测试了表面的坚固性,对抗磨损,有机污染和连续的注射,并在模拟的医院房间中进行验证.
主要成果:
- 在应用后长达7天的时间内,OxiLastTM实现了≥4 log10的细菌数量减少.
- 对各种细菌菌株和接触时间观察到显著的抗菌活性.
- 在模拟磨损,有机污染和连续接种疫苗后,有效性保持不变,在模拟患者护理环境中得到证实.
结论:
- 将OxiLastTM添加到基于的消毒剂中,可以在长达7天的时间内大幅,持续地减少细菌.
- 一致的实验室和模拟的医院结果对感染控制有希望.
- 需要进一步的临床试验来验证在现实世界医疗保健环境中的疗效.
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