估计伊斯兰堡一家三级医院的抗生素消耗,使用世卫组织定义的每日剂量方法
Naila Jabeen1, Waseem Ullah2, Javeria Khalid3
1Department of Pharmacy Practice, Shifa College of Pharmaceutical Sciences, Shifa Tameer-e-Millat University, Islamabad, Pakistan.
Antimicrobial resistance and infection control
|November 24, 2023
概括
抗菌素耐药性是一个越来越令人担忧的问题. 这项研究发现,巴基斯坦一家医院的抗生素处方率很高 (77%),明显超过了世卫组织的标准,并且与AWaRe分类系统不一致.
科学领域:
- 医疗保健管理的管理
- 传染病流行病学 传染病流行病学
- 药理学 药理学是指药理学的学科.
背景情况:
- 不适当使用抗生素会导致抗菌素耐药性,这是一个关键的全球健康问题.
- 巴基斯坦对医院抗生素消费的数据有限.
- 在医院使用抗生素的选择性压力有助于耐药性.
研究的目的:
- 评估伊斯兰堡一家三级医院五年来住院患者的抗生素使用情况.
- 应用世界卫生组织的解剖治疗化学品 (ATC) 分类/定义每日剂量 (DDD) 方法.
主要方法:
- 从2017年1月到2021年12月的药房发行记录的回顾性审查.
- 使用DDD/100-Bed Days (BDs) 公式计算抗生素消耗量.
- 对抗生素使用趋势和相对变化的分析.
主要成果:
- 抗生素消费显示出显著的波动,从2017-2019年下降,在2020年增加,并在2021年下降.
- 77%的入院患者接受了抗生素治疗,远远超过世卫组织<30%的标准.
- 观察组抗生素构成了大多数 (76%) 的处方和消费的抗生素.
结论:
- 医院抗生素消耗数据存在,但与世卫组织的AWaRe指南不一致.
- 处方率远远高于世卫组织的基准,这表明抗生素管理不足.
- 尽管有现有政策,但对抗生素指南的遵守似乎很低.
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