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Updated: Jun 4, 2026

A Lab-On-A-Chip Platform for Stimulating Osteocyte Mechanotransduction and Analyzing Functional Outcomes of Bone Remodeling
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骨质的自下而上的基于挤出的生物制造

Laurens Parmentier1, Sophie D'Haese1, Nathan Carpentier1

  • 1Polymer Chemistry and Biomaterials group (PBM), Centre of Macromolecular Chemistry (CMaC), Department of Organic and Macromolecular Chemistry, Faculty of Sciences, Ghent University, Krijgslaan 281, Building S4-Bis, Ghent, 9000, Belgium.

Macromolecular bioscience
|November 24, 2023
PubMed
概括

这项研究引入了用于骨再生的先进生物打印技术,使用修改过的凝油墨. 这些新材料显著增强了牙髓干细胞中的骨质分化和产量.

关键词:
生物制造是生物制造的方法.生物模仿是什么意思生物物理的线索.骨质炎症患者是什么样的人

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Growth of Cartilage and Bone Tissue

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Bone as Supporting Connective Tissue

Bone tissue forms the internal skeleton of vertebrate animals, providing structure to the body.
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Bone, or osseous tissue, is a connective tissue that has a large amount of two different types of matrix material. The organic matrix is similar to the matrix material found in other connective tissues, including some amount of collagen and elastic fibers. This gives strength and flexibility to the tissue. The inorganic matrix consists of mineral salts— mostly calcium salts— that give the...
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The Bone Matrix

Bone contains a relatively small number of cells entrenched in a matrix of collagen fibers that provide an adherent surface for inorganic salt crystals. Both components of the matrix, organic and inorganic, contribute to the unusual properties of bone. Without collagen, bones would be brittle and shatter easily. Without mineral crystals, bones would flex and provide little support. This can be observed by an experiment: when the minerals of a bone are dissolved by soaking the bone in acid or...
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Bone Formation by Intramembranous Ossification

Intramembranous ossification is one of the two processes involved in the development of bones within an embryo. The flat bones of the face, most of the cranial bones, and the clavicles are formed via this process. During intramembranous ossification, the bones develop directly from sheets of undifferentiated mesenchymal connective tissue.
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Bone Formation by Endochondral Ossification

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