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在肌缩侧面硬化症的口头和非口头流利性

Megan S Barker^1,2, Amelia Ceslis^1,3, Rosemary Argall^1,3

¹School of Psychology, The University of Queensland, Brisbane, Queensland, Australia.

Journal of neuropsychology

|November 24, 2023

概括

肌缩侧面硬化症 (ALS) 患者表现出特定的非语言流利性缺陷,特别是在有意义的手势任务中. 他们的困难不是全球性的,而是涉及在某些任务上随着时间的推移保持性能.

科学领域:

神经科学是一个神经科学.
认知心理学认知心理学

背景情况:

肌缩侧面硬化症 (ALS) 是一种神经退行性疾病,影响认知和行为.
在ALS中,口头流利性缺陷很常见,但对非语言认知功能的理解较少.

研究的目的:

调查ALS相关的认知缺陷是否超出了口语流.
确定观察到的赤字是否代表全球响应产生损害或持续业绩下降.
探索ALS流利性缺陷和冷漠之间的关系.

主要方法:

22名ALS患者和21名对照人完成了口头 (音声,语义) 和非口头 (设计,手势,思想) 流利性任务.
绩效通过整体新品生产和分析"启动"与"维护"阶段来评估.
测量了冷漠度,并与流性表现相关联.

主要成果:

患有ALS的患者在跨任务的整体流性表现上没有表现出总体减少.
特别是在有意义的手势流性方面发现了显著的损害.
"掉落"模式,表明难以保持表现,在语音流性中观察到,但不是其他任务.
漠不关心与流性能的表现没有显著的关系.

结论:

在ALS的认知障碍是特定任务而不是全球性的.
有意义的手势流性的缺陷表明,在获取行动知识方面存在潜在的弱点.
在早期的ALS中,持续的注意力或响应维护可能会在某些认知领域受到选择性的影响.

关键词:

行动语义学行动语义学骨髓缩侧面硬化症 (ALS) 是一种非言语流性非言语流性语言流语言流

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