一种新型的Murraya koenigii提取物具有弹性潜力和抗折性质
Chloé Lorion1, Viviane Bardin1, Sébastien Bonnet1
1Gattefossé SAS, Saint-Priest Cedex, France.
Journal of cosmetic dermatology
|November 24, 2023
概括
一种新的Murraya koenigii提取物通过促进弹性纤维的生产来增强皮肤弹性. 在临床试验中,这种成分明显减少了纹和松,提供了一种创新的抗衰老解决方案.
科学领域:
- 皮肤病学和化学
- 生物技术是生物技术.
- 材料科学 是一种材料科学.
背景情况:
- 弹性生成,即功能弹性纤维的产生,是复杂的,并且很难在体外复制.
- 识别有效的成分,提高皮肤弹性是化学中的一个重大挑战.
研究的目的:
- 为了评估一种新的Murraya koenigii叶茎提取物的弹性增强作用.
- 通过使用3D培养模型在体外和在人体志愿者体内评估提取物的疗效.
主要方法:
- 在3D皮肤等效模型中评估弹性纤维蛋白质合成.
- 利用多光子显微镜和原子力显微镜分析无支架皮肤微组织中的弹性质沉积物和生物力学特性.
- 在体内使用边缘投影成像和临床评分来评估鼻折的严重程度和重力的对面部衰老的影响.
主要成果:
- 在3D皮肤模型中,Murraya koenigii提取物增加了弹性素和纤维素-1表达.
- 在无支架的皮肤微组织中证明了改善组织弹性和有序的弹性网.
- 在98天的局部应用后,显示出鼻和重度的明显减少,并减轻了重力的衰老效应.
结论:
- Murraya koenigii提取物是一种创新的成分,可以提高皮肤弹性.
- 提取物表现出显著的抗衰老特性,特别是在软化方面.
- 这种新型成分适合用于改善皮肤坚和弹性的化品配方.
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