坚持健康和可持续的饮食模式和长期慢性炎症:EPIC - 波茨坦姆队列数据
L Koelman1, C Herpich, K Norman
1Krasimira Aleksandrova, PhD, MPH, Department of Epidemiological Methods and Etiological Research, Leibniz Institute for Prevention Research and Epidemiology, BIPS Achterstr. 30, 28359 Bremen,
坚持EAT-Lancet (EAT-L) 和地中海 (tMDS) 饮食显示,长期炎症生物标志物如化学素和hs-CRP的轻微,无意义的减少. 需要进一步的研究来证实它们在预防疾病中的作用.
科学领域:
- 营养流行病学 营养流行病学
- 炎症的生物标志物
- 饮食模式分析饮食模式分析
背景情况:
- 慢性炎症是许多非传染性疾病的关键因素.
- 饮食模式显著影响炎症反应.
- EAT-Lancet (EAT-L) 和地中海 (tMDS) 饮食因其健康和可持续性益处而得到认可.
研究的目的:
- 调查遵守EAT-L和tMDS饮食模式与长期炎症反应之间的潜在关联.
- 评估饮食坚持随时间变化和炎症生物标志物度之间的关系.
主要方法:
- 一项前性队列研究,涉及EPIC-波茨坦研究的636名参与者.
- 在基线和6.8年后使用食物频率问卷评估了对EAT-L和tMDS的饮食坚持.
- 长期的炎症通过重复测量血中化学素和高灵敏性C反应蛋白 (hs-CRP) 的度.
主要成果:
- 稳定高或增加对EAT-L的坚持与化学素的轻微,不显著的减少有关.
- 增加对tMDS的坚持显示出化学素的轻微减少,而减少坚持与更高的化学素水平有关.
- 与hs-CRP的关联甚至比与chemerin的关联更不明显.
结论:
- 坚持EAT-L和tMDS饮食与长期炎症生物标志物的轻微,非统计学上显著的减少有关.
- 目前的证据表明,这些饮食模式可能不足以在一般人群中针对性预防炎症.
- 需要进一步的研究来探索这些饮食在疾病预防策略中的潜力.
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