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Hao Wang¹, Qi Wu², Lang Yang¹

¹Department of Cardiology, The Second Affiliated Hospital of Nanchang University, Nanchang, China.

Clinical cardiology

|November 24, 2023

概括

血管造影衍生的微循环阻力 (AMR) 有效地预测ST升高心肌梗塞 (STEMI) 患者皮肤穿刺冠状动脉干预后的主要不良心脏事件. 在PCI后的AMR≥250表明不良结果的风险更高.

科学领域:

心脏病学心脏病学
干预心脏病学干预心脏病学
血管生理学血管生理学

背景情况:

冠状动脉微血管功能障碍 (CMD) 的评估对于ST升高心肌梗塞 (STEMI) 是至关重要的.
数量流量比率 (QFR) 衍生的血管学衍生的微循环阻力 (AMR) 显示了CMD的诊断准确性.
有限的研究存在于AMR在STEMI患者的特定应用.

研究的目的:

评估AMR指数在评估STEMI患者的CMD中的实用性.
确定AMR是否可以预测皮肤冠状动脉干预 (PCI) 后STEMI患者的不良心脏事件.

主要方法:

追溯研究包括接受PCI的STEMI患者 (2020年6月 - 2021年9月).
患者分为CMD (n=215) 和非CMD (n=291) 组,与382名患者相匹配.
对主要不良心脏事件 (MACE) 的一年随访.

主要成果:

主要终点 (MACEs) 发生在10.7%的患者中,CMD组的发病率显著更高 (14.1%与7.3%,p=0.042).
在心脏衰竭组中,心脏衰竭的再入院率更高 (7.9%对1.6%,p=0.010).
在PCI后的AMR≥250是MACE的独立预测因子 (HR2.265,p=0.020).

结论:

在PCI后的回顾性AMR评估 (截止值≥250) 预测STEMI患者的1年MACE率显著不同.
AMR作为一种有价值的工具,用于识别患有心脏不良事件风险较高的STEMI患者.

关键词:

在ST升高心肌梗塞 (STEMI) 中.血管造影衍生的微循环阻力 (AMR)冠状动脉微血管功能障碍 (CMD)主要不良心血管事件 (MACE)量化流量比率 (QFR) 是指量化流量比率.

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