氨基酸和癌症:治疗的潜力?
Jéssika M Siqueira1, Maria C M Dela Vega2, Gustavo D Pimentel1
1Faculty of Nutrition, Federal University of Goiás.
Current opinion in clinical nutrition and metabolic care
|November 24, 2023
概括
足够的蛋白质摄入量对于癌症患者至关重要,建议量超过1.0-1.5g/kg/天. 然而,特定氨基酸在癌症营养治疗中的作用和最佳使用仍然不清楚.
科学领域:
- 在瘤学瘤学.
- 营养科学 营养科学
- 生物化学 生物化学
背景情况:
- 癌症的进展往往会导致系统性炎症和蛋白质过代谢患者.
- 营养行为和足够的蛋白质/氨基酸摄入量是癌症管理中的关键考虑因素.
研究的目的:
- 审查蛋白质和氨基酸在癌症患者营养治疗中的影响.
- 评估当前关于瘤学中蛋白质和氨基酸补充剂的建议和证据.
主要方法:
- 对癌症中蛋白质和氨基酸营养治疗研究的文献综述.
- 对蛋白质摄入量和氨基酸补充剂的指导方针和研究结果的分析.
主要成果:
- 较高的蛋白质摄入量 (1.0-1.5 g/kg/day) 通常对癌症患者有益,特别是那些营养不良,肉症或缓冲症患者.
- 单独或组合氨基酸补充 (例如BCAA,谷氨酸,氨酸,肌酸) 的临床益处的证据有限,并且缺乏关于剂量和应用的共识.
结论:
- 癌症患者的蛋白质建议应超过1.0-1.5g/kg/天,动物和植物来源的均衡摄入量.
- 需要进一步的研究来澄清氨基酸补充剂在各种癌症类型和治疗阶段的具体作用,最佳剂量和时间.
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