生物纳米颗粒:抗癌,抗微生物,杀虫剂特性及其对大豆 (Glycine max L) 的影响 种子发芽和苗木生长
Asmaa Abdelsalam1, Heba El-Sayed1, Heba M Hamama2
1Botany and Microbiology Department, Faculty of Science, Helwan University, Helwan 11795, Egypt.
Biology
|November 24, 2023
概括
微生物制造的纳米粒子 (SeNPs) 显示出抗癌和抗菌的特性. 这些生物性SeNP还可以增强大豆生长,打击农业害虫和植物病原体,提供可持续的解决方案.
科学领域:
- 纳米技术纳米技术
- 生物技术是生物技术.
- 农业科学 农业科学
背景情况:
- 纳米颗粒 (SeNPs) 是具有多样化应用的多功能纳米材料.
- 生物合成的SeNPs提供了一个环保的方法来生产纳米粒子.
- 研究菌菌制造的SeNPs的多面生物活动对于其实际实施至关重要.
研究的目的:
- 通过myco-fabrication方法合成纳米粒子 (SeNPs).
- 评估合成的SeNPs的抗癌和抗菌功效.
- 评估SeNPs对大豆 (Glycine max L.) 种子发芽,幼苗生长,棉花叶虫 (Spodoptera littoralis) 死亡率和植物病原菌抑制的影响.
主要方法:
- 纳米颗粒的微型制造.
- 在体外抗癌活性测定对MCF-7乳腺腺癌细胞.
- 针对Proteus mirabilis和Klebsiella pneumoniae的抗菌检测. 这是一个非常好的方法.
- 评估SeNPs对大豆种子发芽和苗木生长参数的影响.
- 对SeNPs对Spodoptera littoralis幼虫的杀虫活性进行评估.
- 对植物病原菌 (Fusarium oxysporum,Rhizoctonia solani,Fusarium solani) 的抑制试验.
主要成果:
- SeNPs表现出显著的抗癌活性,其IC50为1.95μg/mL,对抗MCF-7细胞.
- 菌菌合成的SeNP在20毫克/毫升的剂量下对Proteus mirabilis和Klebsiella pneumoniae产生抗菌作用.
- 低度的SeNPs (1μM) 显著改善了大豆种子的发芽和苗木的生长.
- SeNPs增加了棉花叶虫幼虫的死亡率,中位数致命度为23.08 mg/mL.
- SeNPs有效地抑制了关键植物病原菌的生长:Fusarium oxysporum,Rhizoctonia solani和Fusarium solani.
结论:
- 通过菌体制造合成的生物纳米粒子具有强大的抗癌和抗菌特性.
- 对于农业应用来说,SeNPs显著有前途,包括提高作物产量和害虫管理.
- 这些发现凸显了菌菌制造的SeNP作为癌症治疗,农业和感染控制的可持续剂的潜力.
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