评估与早发性心室综合体有关的心脏功能障碍的早期指标:心肺呼吸能力
Xiaozhu Ma1, Jiangtao Yan1, Wanjun Liu1
1Division of Cardiology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430030, China.
Healthcare (Basel, Switzerland)
|November 24, 2023
概括
心肺运动检测 (CPET) 显示,患有频繁早发性心室复合体 (PVCs) 的患者心肺呼吸能力降低. 这表明CPET可以检测到早期的心脏功能障碍,即使是正常的射出分数.
科学领域:
- 心脏病学 心脏病学
- 运动生理学 运动生理学
背景情况:
- 由于早发性心室复合体 (PVCs) 的心脏功能障碍,很难在早期发现.
- 心肺运动测试 (CPET) 评估运动期间的心脏功能.
研究的目的:
- 调查CPET是否可以在患有频繁PVC的患者中发现早期心脏功能障碍.
- 为了比较PVC患者和健康对照者的心肺呼吸能力.
主要方法:
- 对94名患有频繁PVC的患者和98名匹配的对照患者的CPET数据的回顾性分析.
- 评估心肺呼吸能力,使用氧气吸收峰值 (V'O2峰值),无氧值 (AT) 和其他CPET参数.
- 通过24小时的霍尔特监测诊断的PVC.
主要成果:
- 与对照组相比,PVC患者的V'O2峰值,AT和ΔO2脉冲/Δ工作速率 (ΔV'O2/ΔWR) 显著降低.
- 两组之间没有观察到基线特征或左心室喷射率的显著差异.
- 根据频率 (<10,000,10,000-20,000,>20,000节拍/24小时) 在PVC亚组中没有发现心肺呼吸能力的显著差异.
结论:
- 频繁使用的PVC与心肺呼吸能力的降低有关.
- 在患有PVC的患者中,CPET可以检测到心脏功能障碍的早期迹象,独立于喷射分数.
- 在这项研究中,PVC频率与心肺呼吸系统损伤程度没有相关性.
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