不遵守抗高血压药物治疗的影响
Syed Karam Mustafa Gardezi1, William W Aitken2, Mohammad Hashim Jilani3
1TJ Samson Community Hospital, Glasgow, KY 42141, USA.
Healthcare (Basel, Switzerland)
|November 24, 2023
概括
对高血压的药物不服药显著增加了心血管死亡. 提高遵守率可以防止成千上万的死亡,并降低医疗保健成本,突出需要更好的患者支持.
科学领域:
- 公共卫生 公共卫生
- 心血管医学 心血管医学
- 卫生经济学 卫生经济学
背景情况:
- 药物不服药是医疗保健中的一个重要障碍,特别是在无症状的疾病,如高血压.
- 坚持不良导致患者不良后果,并压迫医疗保健资源.
研究的目的:
- 检查美国血压 (BP) 药物不服药与心血管 (CV) 死亡率之间的关联.
- 确定坚持率对心血管疾病死亡率和医疗保健成本的影响.
主要方法:
- 利用CDC WONDER数据库获取BP药物服药,社会经济因素和心血管结果的数据.
- 采用多变量线性回归模型来评估不遵守和CV死亡之间的关系,控制社会经济变量.
主要成果:
- 血压药物不服药的1%增加与每10万例心脏病死亡总数增加7.13例相关 (95% CI:6.34-7.92).
- 在控制保险获取,医疗补助资格,教育水平,收入和贫困率 (p < 0.001) 之后,这种关联仍然很重要.
结论:
- 在不坚持血压药物治疗和心血管死亡率增加之间存在显著联系.
- 提高遵守率可以防止大量的心血管死亡,并减少医疗保健支出.
- 加强改善药物坚持的努力对于公共卫生和经济原因至关重要.
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