内视网膜变薄 支状视网膜动脉封闭和初级开角玻璃眼之间的比较
Gabriella De Salvo1, Mohamed Oshallah1, Anastasios E Sepetis1
1Ophthalmology Department, University Hospital Southampton NHS Foundation Trust, Southampton SO16 6YD, UK.
Diagnostics (Basel, Switzerland)
|November 24, 2023
概括
内视网膜变薄,特别是在内核层 (INL) 和半球不对称 (HA) 中,可能表明分支视网膜动脉封闭 (BRAO). 这一发现有助于诊断过去的BRAO事件并预防未来的血管事件.
科学领域:
- 眼科医生 眼科 眼科
- 视网膜成像 视网膜成像
- 血管堵塞 血管堵塞
背景情况:
- 分支视网膜动脉封闭 (BRAO) 和初级开角玻璃眼 (POAG) 是影响视网膜的不同的疾病.
- 评估断层扫描视网膜层厚度对于诊断和监测视网膜疾病至关重要.
研究的目的:
- 评估和比较用BRAO对眼睛的断层视网膜层厚度与初级开角玻璃眼 (POAG) 相比.
- 为了确定特定的视网膜层变化,表明BRAO.
主要方法:
- 对27名接受SD-OCT扫描的患者 (16名BRAO,11名POAG) 的回顾性审查.
- 分析包括斑点视网膜神经纤维层 (mRNFL),状细胞层 (GCL),内状层 (IPL),内核层 (INL),神经视网膜边缘 (NRR),环状RNFL和半球不对称性 (HA).
主要成果:
- 在BRAO和POAG组之间,总IPL和INL稀释的统计学显著差异 (分别为p=0.0067和p<0.0001).
- 对于总黄斑变薄,mRNFL,GCL,IPL和INL (p<0.0001) 的显著半球不对称 (HA) 差异.
- 群体之间平均总视网膜稀释,总mRNFL和GCL稀释没有显著差异.
结论:
- 单边内视网膜变薄,特别是INL变薄和HA差>17μm,可能意味着时间BRAO.
- 这些发现可以帮助诊断以前未被诊断的BRAO.
- 早期诊断可能有助于预防进一步的视网膜动脉封闭和脑血管事件.
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