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应用对比增强超声波的定量参数在儿童肝脏的常见良性和恶性病变:一项初步研究

Dan Han¹, Ting Wang¹, Ruiqi Wang¹

¹Department of Ultrasound, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics, Chongqing 400014, China.

Diagnostics (Basel, Switzerland)

|November 24, 2023

概括

量化对比增强超声波 (CEUS) 有效地区分儿科肝病变的良性和恶性病变. 平均传输时间 (mTT) 显示了最高的诊断值,有助于肝脏瘤的识别.

科学领域:

医学成像医学成像
儿科放射学儿科放射学
肝病学肝病学是一种肝病学.

背景情况:

准确区分儿科肝病变对于适当的管理至关重要.
与对比度增强的超声波 (CEUS) 为肝脏损伤评估提供了一种非侵入性成像方式.

研究的目的:

评估从CEUS获得的定量参数的诊断实用性,以区分良性和恶性儿科肝病变.
与定性评估相比,评估定量CEUS分析的性能.

主要方法:

对53名患有肝病变的儿科患者进行了回顾性分析,这些患者接受了CEUS.
使用 SonoLiver® 软件对 CEUS perfusion 模式进行定性和定量分析.
组织病理学,对比度增强的MRI/CT或长期随访作为参考标准.
统计分析包括学生的t测试和ROC曲线分析.

主要成果:

恶性病变主要表现为快速冲洗 (88.57%) 的超增强,而良性病变表现为缓慢冲洗 (94.44%) 的超增强.
像上升时间 (RT),达到峰值时间 (TTP) 和平均过渡时间 (mTT) 这样的定量参数在恶性病变中显著较短 (p < 0.05).
平均传输时间 (mTT) 显示了区分病变类型的最高诊断值 (AUC=0.82).

结论:

定量CEUS分析显著有助于区分儿童的良性和恶性肝病变.
平均传输时间 (mTT) 是确定儿科肝脏瘤的关键定量参数.
定量CEUS分析获得了高准确度 (98.11%),与定性评估 (92.45%) 相比.

关键词:

准确度准确度准确度准确度肝脏的良性和恶性病变.孩子孩子孩子孩子孩子孩子与对比度增强的超声波.定量分析量化分析时间强度曲线.

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