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表观遗传修饰器突变在外围T细胞淋巴瘤中的作用

Adrian-Bogdan Tigu1,2, Anamaria Bancos1,3

  • 1Medfuture Research Center for Advanced Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, 400337 Cluj-Napoca, Romania.

Current issues in molecular biology
|November 24, 2023
PubMed
概括

外周T细胞淋巴瘤 (PTCL) 的表观遗传修饰剂突变,特别是TET2,IDH2和DNMT3A,揭示了新的治疗点. 这些突变增强了PTCL对表观遗传疗法的敏感性,如低甲基化剂和HDAC抑制剂.

关键词:
在PTCL中,PTCL就是PTCL.表观遗传修饰剂 表观遗传修饰剂突变是发生在突变中的突变.治疗疗法治疗疗法治疗疗法

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