不太常见的临床酵母的目录
Estelle Menu1,2, Quentin Filori3, Jean-Charles Dufour3,4
1Laboratoire de Parasitologie-Mycologie, IHU Méditerranée Infection, 13385 Marseille, France.
Journal of fungi (Basel, Switzerland)
|November 24, 2023
概括
本综述列出了导致人类感染的不太常见酵母,详细说明了它们的位置和临床特征. 它更新了酵母分类学,有助于诊断罕见的真菌病.
科学领域:
- 医学真菌学 医学真菌学
- 临床微生物学 临床微生物学
- 酵母分类学 酵母分类学
背景情况:
- 侵袭性真菌病对公众健康构成越来越大的挑战,特别是在免疫功能受损的患者中.
- 虽然Candida物种是常见的罪祸首,但不太常见的酵母被越来越多地认为是机会性病原体.
- 这些不太常见的酵母包括Ascomycota和Basidiomycota中的特定属.
研究的目的:
- 在主要的Candida物种之外对人类致病酵母进行分类.
- 描述与这些不太常见的酵母菌引起的感染相关的解剖部位和临床表现.
- 提供有关酵母物种的最新分类.
主要方法:
- 系统的文献审查和数据库挖掘 (MycoBank,NCBI分类学).
- 鉴定和分类与人类感染相关的真菌种类.
- 报告的酵母隔离点和临床特征的分析.
主要成果:
- 从人类中分离出来的192种不太常见的酵母物种 (127种Ascomycota,65种Basidiomycota) 的综合清单被编制.
- 详细介绍了这些酵母的特定解剖学热带和临床表现.
- 建立了对这些临床相关酵母的最新分类学概述.
结论:
- 不太常见的酵母代表了一个重要的,经常被低估的人类病原体组.
- 了解它们的分布和临床相关性对于准确的诊断和管理至关重要.
- 这项工作是诊断实验室和临床医生管理侵入性真菌感染的宝贵资源.
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