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Updated: Jul 10, 2025

Systems Biology of Metabolic Regulation by Estrogen Receptor Signaling in Breast Cancer
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雌激素受体低阳性乳腺癌:病理和临床前景

Christina Panagiotis Malainou1, Nikolina Stachika1, Aikaterini Konstantina Damianou1

  • 1Oncology Unit, Third Department of Medicine, "Sotiria" General Hospital for Diseases of the Chest, National and Kapodistrian University of Athens, 152 Messogion Avenue, 11527 Athens, Greece.

Current oncology (Toronto, Ont.)
|November 24, 2023
PubMed
概括

低雌激素受体阳性乳腺癌 (BC) 是一个独特的亚型,具有不确定的内分泌治疗益处. 需要更多的研究,特别是在转移环境和临床试验中,以了解和治疗这种BC群.

关键词:
乳腺癌 乳腺癌 乳腺癌内分泌疗法是一种内分泌疗法.雌激素受体的受体是雌激素受体.雌激素受体低阳性乳腺癌三重阴性乳腺癌是什么

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Nuclear receptors, or NRs, are unique transcription factors that regulate gene transcription and affect the cellular pathways involved in reproduction, development, or metabolism. Their ability to be stimulated by small lipophilic ligands and control vital cellular processes makes them ideal drug targets. Nearly 10-15% of currently prescribed drugs target these receptors.
About 48 different soluble family members of nuclear receptors are identified that can be divided into two main classes:
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