控制营养状况评分作为预测慢性阻塞性肺部疾病老年患者恶化风险的预测指标
Aurelio Lo Buglio1, Giulia Scioscia2, Francesco Bellanti1
1Department of Medical and Surgical Sciences, Institute of Internal Medicine, University of Foggia, Policlinico of Foggia, 71122 Foggia, Italy.
控制营养状况 (CONUT) 评分有效预测慢性阻塞性肺病 (COPD) 的老年患者的频繁恶化. 高CONUT分数表明恶化的风险更高,有助于临床管理.
科学领域:
- 老年病的医生 老年病的医生
- 肺部病理学 肺部病理学
- 临床营养学 临床营养学
背景情况:
- 控制营养状况 (CONUT) 评分评估营养状况并预测不良结果.
- 对于老年慢性阻塞性肺病 (COPD) 患者的CONUT评分有用性存在有限的数据.
- 频繁的恶化严重影响COPD患者的预后和医疗负担.
研究的目的:
- 评估CONUT评分在预测老年COPD患者频繁恶化的有效性.
- 确定CONUT得分是否可以作为COPD恶化预后工具.
主要方法:
- 对222名65岁及以上的慢性肺炎患者进行了回顾性分析.
- 根据恶化的频率 (≥2次恶化或≥1次住院) 和CONUT分数 (低<5对高≥5) 分类的患者.
- 统计分析,包括多变量分析,以确定频繁恶化的预测因素.
主要成果:
- 67.2%的频繁恶化症具有高的CONUT分数.
- 高的CONUT分数与较高的CAT分数,较低的FEV1和更严重的GOLD阶段相关.
- 一个CONUT分数≥5是频繁恶化最强的独立预测因素 (OR20.740,p<0.001).
结论:
- 康得分在预测老年COPD患者频繁恶化时具有显著的预后价值.
- CONUT评分作为一种有价值的工具,用于识别患恶化高风险的个体.
- 需要进一步的多中心前性研究来验证在较大的COPD队列中CONUT分数切断值.
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