首要预防犬类无皮炎:打破循环-A叙事审查
Beatriz Fernandes1,2,3, Susana Alves1,2, Vanessa Schmidt4
1CIISA-Centre for Interdisciplinary Research in Animal Health, Faculty of Veterinary Medicine, University of Lisbon, 1649-004 Lisbon, Portugal.
Veterinary sciences
|November 24, 2023
概括
预防犬皮炎 (cAD) 对狗和主人来说至关重要. 迫切需要对主要预防策略的研究,重点关注皮肤屏障,这可能有利于人类医学.
科学领域:
- 兽医皮肤病学 兽医皮肤病学
- 免疫学 免疫学 免疫学
- 比较医学是一种比较医学.
背景情况:
- 狗皮炎 (cAD) 影响多达30%的狗,影响它们和它们的主人的生活质量.
- cAD与人类亚托皮性皮肤炎 (hAD) 具有复杂的病原体,涉及遗传和环境因素.
- 目前的cAD治疗可以治疗临床症状,但有局限性,并且可能昂贵.
研究的目的:
- 强调对犬类亚托皮性皮肤炎 (cAD) 的初级预防的重要性.
- 突出皮肤屏障在cAD病变发生过程中的关键作用.
- 倡导增加对cAD初级预防策略的研究.
主要方法:
- 对有关犬类和人类亚托皮性皮肤炎的现有文献的综述.
- 分析皮肤屏障功能障碍在cAD和hAD中的作用.
- 在hAD与cAD中预防研究的比较.
主要成果:
- 皮肤屏障功能障碍是hAD和cAD的关键因素.
- hAD初级预防研究显示,增强皮肤屏障具有前途.
- 与hAD相比,对cAD的初级预防研究显著欠发达.
结论:
- 首要预防cAD对于改善狗和主人福祉至关重要.
- 对cAD预防策略的进一步研究是及时和必要的.
- 在cAD预防方面的发现可能对人类皮肤病学研究具有翻译性益处.
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