一种新的无酒精有机酸性手消毒剂对食源性病原体的有效性
Gözde Bayer1, Amirreza Shayganpour2, Ilker S Bayer2
1DS Bio ve Nanoteknoloji A. Ş, Lavida City Plaza 45/7, 06530 Ankara, Türkiye.
Toxics
|November 24, 2023
概括
这项研究引入了一种新型无酒精的洗手液,该洗手液配制有机酸,硫酸和波维-. 这种新型消毒剂有效地减少了细菌,并显示出对温和,延长皮肤保护的承诺.
科学领域:
- 化学 化学 化学
- 微生物学 微生物学
- 皮肤病学 皮肤病学
背景情况:
- 由于COVID-19的流行,人们对手部消毒剂的需求增加了.
- 基于酒精的消毒剂存在诸如皮肤损伤和易燃性等风险.
- 为了安全性和有效性,人们正在寻找无酒精替代品.
研究的目的:
- 开发和评估一种有效的无酒精手洗手液.
- 评估有机酸,硫酸和波维-的协同抗菌作用.
- 为了确定配方的稳定性和皮肤友好的特性.
主要方法:
- 使用乳酸,酸和azelaic酸,硫酸和povidone-iodine的水性手消毒剂的配方.
- 在体外测试对 *Clostridium botulinum*, *Escherichia coli*, *Listeria monocytogenes* 和 *Staphylococcus aureus* 进行检测.
- 超过60天的稳定性测试,包括对三二离子形成的分析.
主要成果:
- 有机酸表现出协同作用的抗菌活性,实现CFU/mL的3-log降低.
- 添加波维-和硫酸增强了疗效,从而减少了4-log.
- 手部消毒剂在60天内保持稳定,并观察到三化离子的释放.
结论:
- 开发的无酒精手洗剂提供强大的抗菌作用,对常见的食源性病原体.
- 该配方是稳定的,并且由于释放三化离子,可以提供延长的保护.
- 酸和乳酸有助于化品和抗氧化剂的特性,表明一个温和,皮肤友好的产品.
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