在对COVID-19的临床检测方面取得的最新进展
Sungwoon Lee1, Liyan Bi2, Hao Chen3
1Department of Chemistry, Chung-Ang University, Seoul 06974, South Korea. lxchen@yic.ac.cn.
Chemical Society reviews
|November 24, 2023
概括
便携式微流体设备为COVID-19等流行病提供了快速护理点测试 (POCT). 整合光学阅读器和人工智能可以提高诊断准确度,并为未来的全球卫生挑战做好准备.
科学领域:
- 生物医学工程 生物医学工程
- 诊断 诊断 诊断 诊断
- 公共卫生 公共卫生
背景情况:
- 微流体设备正在推进诊断,使得便携式和智能手机兼容的测试成为可能.
- 目前针对COVID-19的临床点检测 (POCT) 面临敏感度的限制,导致虚假阴性.
研究的目的:
- 审查针对COVID-19的基于微设备的POCT的最新进展.
- 探索光学检测方法和人工智能集成,以增强流行病传感.
主要方法:
- 微设备的审查:横流,垂直流,微流体通道,纸质设备.
- 对光学检测策略的分析:光,SERS,SPR,可穿戴传感器.
- 讨论人工智能集成用于下一代流行病检测.
主要成果:
- 与光学阅读器集成的微设备提高了POCT灵敏度.
- 像光和SERS这样的光学检测方法对COVID-19 POCT.有效.
- 人工智能整合有望实现先进的流行病传感能力.
结论:
- 增强的POCT战略对于管理传染病和未来的流行病至关重要.
- 人工智能驱动的微流体诊断是迈向全球健康安全的重要一步.
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