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部分切除术后膜体积和功能状态的纵向变化:一个回顾性队列研究
Longbin Xiong1,2,3, Xiangpeng Zou1,2,3, Xin Luo1,2,3
1Departments of Urology.
International journal of surgery (London, England)
|November 24, 2023
概括
部分切除术 (PN) 后,膜体积 (RPV) 显著下降,特别是在严重的急性损伤时. 这种RPV的减少与更快的膜过率 (GFR) 的下降有关,特别是在超重的患者中.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 放射学 放射学是一门学科.
背景情况:
- 部分切除术 (PN) 导致立即的ipsilateral侧膜体积 (RPV) 减少.
- 随后的RPV变化及其与快速膜过率 (GFR) 在PN后下降的联系尚不清楚.
研究的目的:
- 为了研究从1-12个月到PN后≥1年的ipsilateralRPV和功能变化.
- 确定预测RPV下降的因素及其与GFR下降的相关性.
主要方法:
- 对367名接受PN治疗的患者进行了回顾性审查.
- 3DCT/MRI用于RPV计算;急性损伤 (AKI) 评估的频谱得分.
- GFR快速下降定义为>3毫升/分钟/1.73米2/年;用于预测因素的线性/逻辑回归.
主要成果:
- 在平均21.1个月的随访期间,中位数的ipsilateral RPV从118.7毫升显著下降到111.8毫升.
- 间隔时间和频谱得分预测了RPV下降率.
- GFR快速下降 (27.5%的患者) 与每年RPV下降率和超重状态有关.
结论:
- 侧RPV显示PN后温和但显著下降,特别是在更严重的AKI.
- GFR的快速下降与ipsilateral RPV的减少有关,特别是在超重的个体中.
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