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相关概念视频

Neuroplasticity01:01

Neuroplasticity

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Neuroplasticity reflects the brain's remarkable capacity to adapt and evolve, responding dynamically to learning, experiences, or injury by reorganizing its neural circuitry. This reorganization involves creating new neural connections and refining old ones through a series of biological processes that contribute to the brain's lifelong development and adaptability.
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Long-term Potentiation01:35

Long-term Potentiation

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Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre- and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
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Brain Imaging01:14

Brain Imaging

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Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
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Neurogenesis and Regeneration of Nervous Tissue01:15

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In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
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相关实验视频

Updated: Jul 10, 2025

Perspectives on Neuroscience
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利用神经可塑性的利用

Sophia Vinogradov1

  • 1Department of Psychiatry and Behavioral Science, University of Minnesota Medical School, United States.

Psychiatry research
|November 24, 2023
PubMed
概括
此摘要是机器生成的。

基于神经科学的认知训练通过增强大脑可塑性,改善了精神分裂症患者的工作记忆和临床功能. 这种方法为认知缺陷提供了一个有希望的治疗途径.

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科学领域:

  • 神经科学是一个神经科学.
  • 精神病学是一个精神病学.
  • 认知科学 认知科学

背景情况:

  • 认知障碍是精神分裂症治疗中未得到满足的重要需求.
  • 神经可塑性研究已经为像阅读障碍这样的疾病提供了认知训练.

研究的目的:

  • 调查针对听觉皮层可塑性的认知训练是否可以改善精神分裂症患者的工作记忆.
  • 评估强化认知训练对认知和临床结果的影响.

主要方法:

  • 实验性治疗学研究使用专注,努力和密集的认知训练协议.
  • 评估心理物理,认知,血清BDNF,抗胆固醇负担,电生理学,大脑激活和体积变化.
  • 评估6个月的临床功能.

主要成果:

  • 认知训练导致近距离和远距离认知能力的改善.
  • 观察到血清BDNF水平的增加以及大脑中的积极的神经塑性变化.
  • 抗胆固醇负荷的负面影响被注意到;积极反应者表现出更好的临床功能.

结论:

  • 基于神经科学的认知训练可以利用皮质可塑性来治疗精神分裂症.
  • 了解和应用神经可塑性的基础科学对于精神病治疗至关重要.
  • 这种方法显示了改善精神分裂症认知缺陷和临床结果的潜力.