菌抑制剂是否会改变织品上的微生物社区结构和抗生素耐药性基因配置文件?
Ningyuan Yao1, Wei Li2, Lanfang Hu2
1College of Science, The Australian National University, Canberra, ACT 2601, Australia.
The Science of the total environment
|November 24, 2023
概括
织品上的菌抑制剂会改变微生物群落和抗生素耐药性基因 (ARG). 帕拉二二 (PDCB) 显著减少了细菌多样性,同时增加了真菌多样性和ARG.
科学领域:
- 环境科学 环境科学
- 微生物学 微生物学
- 织科学 织科学
背景情况:
- 模具抑制剂在织品中广泛用于保存.
- 它们对织微生物群落和抗生素耐药性基因 (ARG) 的影响尚不清楚.
研究的目的:
- 研究三种模具抑制剂 (二甲 (PDCB),甲和天然球) 对织微生物群落和ARG概况的影响.
- 探索潜在的微生物机制.
主要方法:
- 使用了高通量定量PCR和Illumina测序.
- 细菌和真菌社区结构和ARG配置文件的分析.
主要成果:
- PDCB减少了细菌多样性,但增加了真菌多样性和ARG丰度.
- 纳夫他林和坎佛对细菌多样性有轻微影响,但改变了真菌群落.
- 所有的抑制剂都改变了ARG概况,可能是通过微生物继承和水平基因转移.
结论:
- 菌抑制剂显著影响织品微生物生态和ARG概况.
- PDCB显示出最明显的效应,由于丰富的宿主细菌增加了ARG.
- 这些发现对于选择安全的织模具抑制剂和评估微生物风险至关重要.
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