手术用于脑病患者的认知改善
John R McLaren1, Kristopher T Kahle2, R Mark Richardson3
1Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA; Harvard Medical School.
Neurosurgery clinics of North America
|November 24, 2023
概括
手术可以增强患有脑病 (EEs) 的儿童的神经发育. 即使没有耐药性发作,手术也可以使这些患者的认知能力得到改善.
科学领域:
- 儿科神经学 儿科神经学
- 神经发育障碍 神经发育障碍
- 发病学 (Epileptology) 是一个专业的学科.
背景情况:
- 性脑病变 (EEs) 的特点是频繁的型活动导致神经发育障碍.
- 目前对EEs的治疗模式往往侧重于药理干预.
研究的目的:
- 审查证据支持手术作为神经发育干预在患有ES的儿童.
- 突出外科手术治疗的潜在好处超出了控制.
主要方法:
- 系统性审查现有关于儿科EEs手术结果的文献.
- 一个患有EE的患者接受了成功的诊断和治疗手术的案例说明.
主要成果:
- 有证据表明,手术可以对患有ES的儿童的神经发育产生积极影响.
- 手术干预在本例中导致了显著的认知改善,即使没有耐火性.
结论:
- 手术是改善ES儿童神经发育结果的可行的治疗选择.
- 仅仅是认知能力的提高就足以成为推在专门中心进行手术干预的充分迹象.
相关概念视频
Arteries of the Lower Limbs
192
Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
192
Electroconvulsive Therapy
44
Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early...
44
Psychosurgery
57
Psychosurgery, the surgical alteration or permanent removal of brain tissue to alleviate severe psychological conditions, stands as one of the most radical and controversial treatments in the history of mental health care. Its development and application have evolved significantly, marked by dramatic shifts in scientific understanding and ethical perspectives.
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...
57
Antiepileptic Drugs: Glutamate Antagonists
380
Glutamate is a fundamental neurotransmitter in the central nervous system, playing a vital role in neuronal communication and various cognitive processes. Glutamate stands as the principal excitatory neurotransmitter in the brain. Its presence is crucial for the communication between neurons, underpinning essential processes such as synaptic transmission, neuronal excitability, and plasticity. These functions are vital for higher-order cognitive processes, including learning and memory. The...
380


