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Updated: Jul 10, 2025

Hybrid De Novo Genome Assembly for the Generation of Complete Genomes of Urinary Bacteria using Short- and Long-read Sequencing Technologies
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Published on: August 20, 2021

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评估长期阅读的真核生物基因组的新组装工具:洞察和考虑

Bianca-Maria Cosma1, Ramin Shirali Hossein Zade1, Erin Noel Jordan1,2

  • 1Delft Bioinformatics Lab, Intelligent Systems, Delft University of Technology, 2628 XE, Delft, The Netherlands.

GigaScience
|November 24, 2023
PubMed
概括

选择正确的基因组组合算法对于真核生物基因组项目至关重要. 这项研究对长读汇编器进行了基准测试,发现Flye是PacBio CLR和ONT的最佳选择,而Hifiasm/LJA则是PacBio HiFi的最佳选择.

关键词:
在 de novo 组装.基准测试 (benchmarking) 是一种比较的方法.简介:真核生物基因组.第三代测序系统是第三代测序系统.

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