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用Risperidone治疗的妄想性感染:一系列27名患者
Nycolle L K O Guedes1, Alexandre J Dwan2, Paula Gerlero1
1Departments of Dermatology.
Clinical and experimental dermatology
|November 24, 2023
概括
利斯佩里能有效治疗妄想性感染 (DI),一种患者错误地认为自己被感染的情况. 这项研究发现RISPERIDONE是一种耐受性良好且安全的治疗选择,用于控制DI症状.
科学领域:
- 皮肤病学 皮肤病学
- 精神病学是一个精神病学.
- 药理学 药理学是指药理学的学科.
背景情况:
- 妄想感染 (DI) 患者通常会抵抗精神活性药物治疗.
- 皮莫齐德是DI的前一线药物,但现在不那么常见了.
- 利斯佩里用于DI的使用始于1995年,之前的研究审查了其有效性.
研究的目的:
- 为了研究用RISPERIDONE治疗的幻觉感染患者的特征和治疗结果.
- 这项研究是在巴西圣保罗的一所大学医学中心进行的.
主要方法:
- 对被诊断患有DI并接受RISPERIDONE治疗的患者进行了回顾性分析.
- 收集的数据包括患者人口统计和治疗结果.
- 研究期间是从2016年起在皮肤学大学诊所进行的.
主要成果:
- 这项研究包括27名患者 (20名女性,7名男性).
- 里斯比里的维护剂量从每周三次1mg到每天8mg不等.
- 大多数患者的症状得到控制,只有一个没有反应. 由于副作用,四名患者需要降低剂量,而三名患者尽管反应良好,但转换了抗精神病药物.
结论:
- 里斯佩里在治疗妄想性感染 (也称为妄想性寄生虫病) 中表现出有效性,良好的耐受性和安全性.
- 长期控制症状需要对患者进行适当的随访.
- 里斯佩里为管理这种具有挑战性的疾病提供了一种有价值的治疗选择.
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