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Updated: Jul 10, 2025

Yeast As a Chassis for Developing Functional Assays to Study Human P53
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失去p53功能促进了DNA损伤诱导的核活性纤维的形成

Takeru Torii1, Wataru Sugimoto1, Katsuhiko Itoh1

  • 1Faculty of Frontiers of Innovative Research in Science and Technology (FIRST), Konan University, Kobe, 650-0047, Japan.

Cell death & disease
|November 24, 2023
PubMed
概括

瘤抑制剂p53和caspase-1通常会在DNA损伤后抑制核活性丝的形成. 抑制这种途径或表达nLifeact-GFP促进了线索的形成,可能提高癌症治疗的疗效.

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