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Updated: Jul 10, 2025

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评估结合生物功能的17种方法与GWAS总结统计数据以加快发现,表明高灵敏度和高积极预测值之间的权衡

Amy Moore1, Jesse A Marks2, Bryan C Quach2

  • 1Genomics and Translational Research Center, RTI International, Research Triangle Park, NC, 27709, USA. almoore@rti.org.

Communications biology
|November 24, 2023
PubMed
概括

功能权重方法可以在不增加样本大小的情况下在全基因组关联研究 (GWAS) 中识别新的遗传关联. 一些使用类型学和表达定量特征位置的方法显示出高准确性来命名复杂特征的变体.

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