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睡眠持续时间与儿童的肝硬化有关,这取决于身体脂肪度
Begoña de Cuevillas1, Judith Lubrecht2,3, Santiago Navas-Carretero4,5,6
1Center for Nutrition Research, Department of Nutrition, Food Sciences and Physiology, School of Pharmacy and Nutrition, University of Navarra, Irunlarrea 1, 31008, Pamplona, Spain. bdecuevilla@unav.es.
European journal of pediatrics
|November 24, 2023
概括
睡眠时间与超重/肥胖儿童脂肪肝风险有关. 睡眠时间调解了体脂分布和肝硬化指数之间的关系,为预防和治疗提供了洞察力.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 肝病学 肝病学是一种肝病学.
- 睡眠医学 睡眠医学
背景情况:
- 睡眠时间是儿童超重和肥胖的一个重要因素.
- 儿童和青少年的过度肥胖与肝脏健康状况密切相关.
- 睡眠时间可能是管理儿科脂肪肝疾病的可修改的生活方式因素.
研究的目的:
- 为了研究睡眠,肝脏健康和儿童和青少年身体脂肪分布之间的关系.
- 分析睡眠时间如何调解身体脂肪分布和肝硬化之间的相互作用.
- 探索睡眠在预防和治疗过度脂肪和相关肝病的相关性.
主要方法:
- 一项涉及854名超重/肥胖儿童和青少年 (2-18岁) 的横截面研究.
- 人类测量,临床和生化测量的集合.
- 评估体脂分布和计算肝脏标志物,包括肝脏肥胖症指数;研究睡眠时间调度.
主要成果:
- 在超重和肥胖儿童之间观察到脂肪肝病得分的显著差异 (p < 0.05).
- 与超重儿童相比,肥胖儿童的肝硬化指数大约高出15% (p < 0.001).
- 发现睡眠时间调解了39%的身体脂肪分布和肝脂肪症指数之间的关系,这取决于BMI z-score.
结论:
- 睡眠时间与体重过重/肥胖的儿科人群中身体脂肪分布和肝脏肥胖指数之间的关系有关.
- 研究结果强调了睡眠监测在管理过度脂肪和预防儿童和青少年脂肪肝疾病方面的潜在作用.
- 睡眠时间成为儿童肥胖和相关肝脏疾病的综合管理策略中需要考虑的关键因素.
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