儿科胸部神经性瘤的胸腔镜 - - 欧洲多中心研究
Jean François Lecompte1, Sabine Sarnacki2, Sabine Irtan3
1Fondation Lenval, University Nice Côte d'Azur, 06200 Nice, France.
Cancers
|November 25, 2023
概括
胸腔镜检查是儿科胸部神经性瘤的安全手术,在某些情况下提供了良好的结果. 手术成功取决于图像定义的风险因素,而瘤生物学和组织学则影响瘤学结果.
科学领域:
- 儿科手术 儿科手术
- 胸部瘤学 胸部瘤学
- 最少侵入性的手术
背景情况:
- 胸部神经性瘤是儿童患者的一个重大问题.
- 准确的评估和有效的治疗对于改善患者的治疗结果至关重要.
研究的目的:
- 评估胸腔镜在治疗儿科胸部神经性瘤中的疗效和结果.
- 确定影响手术和瘤结果的因素.
主要方法:
- 在15个欧洲中心 (2000-2020年) 进行了对119名小儿科患者进行胸腔镜检查胸部神经性瘤的回顾性审查.
- 评估手术前数据,并发症和结果,包括图像定义风险因素 (IDRF) 和对化疗的反应.
- 分析病理发现,复发率和生存数据.
主要成果:
- 胸腔镜检查对119名患者进行 (平均年龄为4岁).
- 并发症包括胸和肺; 长期问题包括霍纳综合征和结症.
- 复发与瘤生物学,组织学和化疗相关 (p=0.034,<0.001,0.015);残留与术前IDRF和化疗相关 (p=0.04,0.020).
结论:
- 胸腔镜检查是一种安全有效的方法,用于选择的儿科胸部神经性瘤.
- 手术结果与图像定义的风险因素有关.
- 瘤结局受到瘤组织学和生物学的影响.
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