灵敏的喘:还在船上吗?
Dina Visca1,2, Francesco Ardesi2, Rosella Centis3
1Division of Pulmonary Rehabilitation, Istituti Clinici Scientifici Maugeri, IRCCS, 21049 Tradate, Italy.
Biomedicines
|November 25, 2023
概括
易碎性喘是一种严重的喘表型,可能为患者分层和管理提供新的见解. 尽管数据有限,但它的历史定义可能与现代临床实践有关.
科学领域:
- 肺部病理学 肺部病理学
- 临床医学 临床医学
- 呼吸系统医学 呼吸系统医学
背景情况:
- "易碎喘"一词在21世纪初描述了一种危及生命的喘表型,但从那时起就不再使用了.
- 本综述重新审视了易碎性喘的历史概念,以评估其在当代临床环境中的潜在相关性.
研究的目的:
- 探索"易碎喘"的历史定义和特征.
- 评估性喘概念对当前喘管理策略的适用性.
- 确定该术语是否可以为患者分层和改善疾病控制提供新的途径.
主要方法:
- 使用医学科目标题 (MeSH) 和自由文本术语进行了非系统的文献搜索.
- 没有对研究设计或出版类型的限制,以确保全面的数据检索.
主要成果:
- 目前关于脆性喘的数据很少,只有很少的研究可用.
- 从历史上看,脆性喘被分为两种类型:一种是尽管高剂量治疗,但具有广泛的峰值呼气流 (PEF) 变异性,另一种是患有看似受控喘的患者突然发作.
- 这些子类的定义特征和流行数据仍然有限.
结论:
- 喘的严重程度和控制目前由各种术语定义.
- 重新评估"易碎喘"的历史概念可能为患者分层提供有价值的见解.
- 研究这种表型可能会导致改善严重或难以控制的喘的管理策略.
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