重温水果过敏:全球流行,诊断和当前管理
Thanachit Krikeerati1,2, Pongsawat Rodsaward3,4, Jutamard Nawiboonwong5
1Division of Allergy and Clinical Immunology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.
Foods (Basel, Switzerland)
|November 25, 2023
概括
本综述提供了水果过敏患病率的全球概述,强调了在花粉食物过敏综合征 (PFAS) 中交叉反应的作用,并探索了关键的过敏原和管理策略.
科学领域:
- 免疫学 免疫学 免疫学
- 过敏学 过敏学
- 食品科学 食品科学 食品科学
背景情况:
- 果物过敏存在各种症状,从轻微的口腔过敏综合征到严重的过敏反应.
- 对于水果过敏的人口水平流行数据有限,通常基于单中心研究.
- 花粉食物过敏综合征 (PFAS) 是一个主要的机制,由花粉和食物过敏原之间的交叉反应驱动,由于类似的表观.
研究的目的:
- 通过系统的文献审查,提供对水果过敏患病率的全球概述.
- 探索植物性食品中的关键过敏原分子及其交叉反应模式.
- 提供对管理建议的见解,并比较当前的指南.
主要方法:
- 对2009年至2023年间发表的研究进行了系统的文献搜索.
- 在包含的研究中分析潜在的分析偏差.
- 对过敏原成分和交叉反应性的分子过敏学数据的审查.
主要成果:
- 确定了水果过敏的各种临床表现,包括全身反应.
- 强调了交叉反应和花粉食物过敏综合征 (PFAS) 在水果过敏中的重要性.
- 详细介绍了重要的过敏原分子和交叉反应模式.
结论:
- 果物过敏是一种严重的健康问题,表现各异.
- 了解交叉反应和特定的过敏原对于有效的管理至关重要.
- 对比和完善管理指南可以改善临床决策.
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