甜汁加工副产品提取物:一种空管理替代赫西丁
Suvro Saha1,2, Christine Boesch1, Joanne Maycock1
1School of Food Science and Nutrition, Faculty of Environment, University of Leeds, Leeds LS2 9JT, UK.
Biomolecules
|November 25, 2023
概括
工业甜废弃物提取物 (ISOWE) 显示出有前途的作为化 (CHX) 的天然替代品,用于治疗牙损伤. 与CHX相比,ISOWE证明了较低的毒性和更好的口腔微生物群的保存.
科学领域:
- 生物化学 生物化学
- 微生物学 微生物学
- 牙科研究 牙科研究
背景情况:
- 牙损是一个广泛的全球健康问题,影响所有年龄组.
- 目前的治疗方法,如赫西丁 (CHX),可能会产生不良影响,包括毒性和破坏口腔微生物群.
研究的目的:
- 评估工业甜废弃物提取物 (ISOWE) 作为治疗牙损伤中的CHX的潜在替代品.
- 为了比较ISOWE,CHX及其组合的细胞毒性和抗菌疗效.
主要方法:
- 对口腔上皮细胞进行了细胞毒性测定,用于ISOWE和CHX.
- 使用7天复杂的口服生物膜模型评估了抗微生物药物的有效性.
- 分析了对致病性和与健康相关的口腔微生物的影响.
主要成果:
- 与CHX不同,ISOWE没有显著的毒性,而CHX降低了细胞活力.
- ISOWE证明了对病原性物种的选择性抗微生物作用,保留了有益的口腔细菌.
- 结合ISOWE和0.1%的CHX治疗,在空性生物膜中显示出与0.2%的CHX单独治疗相比的疗效.
结论:
- ISOWE是一种有前途的天然抗原剂,具有良好的安全性.
- ISOWE为致病性细菌提供了增强的选择性,可能保持口腔微生物组平衡.
- ISOWE代表了一个可行的,少有毒的CHX替代品,用于牙损伤管理.
相关概念视频
01:23Hand hygiene
3.3K
Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...
Hand washing...
3.3K
01:37The Citric Acid Cycle: Overview
17.5K
In aerobic organisms, the citric acid cycle is the second stage of cellular respiration wherein molecules derived from the breakdown of carbohydrates, proteins, and fats are oxidized into carbon dioxide and energy. This process is also known as the tricarboxylic acid (TCA) cycle as the first product of the cycle, citric acid, contains three carboxyl groups in its structure. Alternatively, this cycle is also referred to as the Krebs cycle, in honor of its discoverer Sir Hans Krebs.
The citric...
The citric...
17.5K