在mGluR5自身抗体介导脑炎后,持续的口头记忆编码和回忆缺陷
Niels Hansen1,2, Kristin Rentzsch3, Sina Hirschel1
1Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, Von-Siebold-Str. 5, 37075 Goettingen, Germany.
Brain sciences
|November 25, 2023
概括
一名患者在接受抗甲基酸盐受体5型 (mGluR5) 脑炎治疗后,经历了持续的口头记忆缺陷. 这表明mGluR5抗体可能会导致经过急性炎症的持续性认知障碍.
科学领域:
- 神经免疫学 神经免疫学
- 神经精神病学是一种神经精神病学.
- 突触性可塑性 突触性可塑性
背景情况:
- 甲基酸盐受体5型 (mGluR5) 对突触可塑性和记忆力至关重要.
- 对mGluR5的自身抗体与认知障碍,特别是记忆力缺陷有关.
- 与mGluR5抗体相关的脑炎可能导致显著的神经功能障碍.
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