在F18中的氧葡萄糖-正子发射断层扫描 (FDG-PET) 扫描中的多吸收模式 改善恶性多溢出的识别
Samuel E Cohen1, Jaime Betancourt2,3, Guy W Soo Hoo2,3
1Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
立方体发射断层扫描 (FDG-PET) 扫描可以高精度地识别恶性多叶流液 (MPE). 这种成像技术可能会减少对怀疑MPE的患者进行侵入性诊断程序的需要.
科学领域:
- 在瘤学瘤学.
- 放射学 放射学是一门学科.
- 肺部病理学 肺部病理学
背景情况:
- 恶性流 (MPE) 诊断通常需要侵入性手术,如胸腔切除或活检.
- 诊断MPE可能具有挑战性,往往需要重复的侵入性采样.
- F-Fluorodeoxyglucose-Positron Emission Tomography (FDG-PET) 可以评估恶性瘤的参与,并可能有助于避免侵入性手术.
研究的目的:
- 评估FDG-PET在诊断MPE中的实用性.
- 为了确定FDG-PET模式在识别胸膜恶性瘤中的准确性.
- 评估FDG-PET是否可以避免需要进一步的侵入性诊断程序.
主要方法:
- 已确认恶性瘤和疑似MPE的患者的回顾性审查.
- 对接受了细胞学和FDG-PET诊断胸腔切除的患者的分析.
- 对FDG-PET吸收模式的盲目审查和分类.
主要成果:
- 在100名患者中,有70人确诊MPE. 在76名患者中观察到积极的FDG-PET吸收.
- FDG-PET显示与恶性组织学有76%的一致性.
- 阳性肺部FDG-PET对MPE具有91%的阳性预测值,而封闭模式显示100%的PPV.
结论:
- 积极的FDG-PET膜吸收是识别MPE的可靠方法.
- 在FDG-PET上的封闭模式对恶性瘤具有很高的预测性.
- FDG-PET可能会减少对额外的侵入性手术的需要,即使初始细胞学是负的.
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