韩国慢性咳的抗咳处方中的性别差异
Jinkyeong Park1, Yoonki Hong2, Ji Young Hong3,4
1Department of Pulmonary, Allergy and Critical Care Medicine, Kyung Hee University Hospital at Gangdong, School of Medicine, Kyung Hee University, Seoul 05278, Republic of Korea.
这项研究揭示了韩国慢性咳特征和治疗坚持的性别差异. 有效的慢性咳管理需要个性化,性别特定的方法.
科学领域:
- 肺部病理学 肺部病理学
- 流行病学 流行病学
- 药理学 药理学是指药理学的学科.
背景情况:
- 慢性咳影响了相当一部分人口,性别之间有不同的特征和预后.
- 了解这些基于性别的差异对于开发有效的治疗策略至关重要.
研究的目的:
- 为了研究和比较男性和女性患者之间慢性咳的特征和预后,处方了抗咳剂.
- 为了确定与治疗中止和慢性咳重入医院相关的因素.
主要方法:
- 对韩国医疗保险审查和评估 (HIRA) 索赔数据的回顾性分析.
- 包括患有慢性咳的成年患者 (≥18岁) 连续处方抗咳药超过两个月 (2017年1月至2019年6月).
- 利用考克斯回归分析来确定重新入院的风险因素.
主要成果:
- 在女性 (9.7%) 和男性 (6.2%) 之间,不明原因咳的发病率更高,而在男性 (16.8%) 和女性 (14.3%) 之间,持续咳的发病率更高.
- 女性更有可能在治疗后停止服用药物;只有53.9%的患者坚持服用药物超过6个月.
- 60年代-70年代的年龄和解释性咳与更高的再接收风险有关.
结论:
- 在男性和女性之间,慢性咳的特征和处方模式存在明显的差异.
- 考虑性别,年龄和潜在疾病的个性化治疗方法对于慢性咳管理至关重要.
- 需要进一步的研究来评估性别特异性治疗和潜在疾病控制的疗效.
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