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甲型大动脉剖析的内血管治疗:使用重建的时间到事件数据进行系统审查和元分析
Konstantinos S Mylonas1,2, Ioannis Zoupas2,3, Panagiotis T Tasoudis3
1Department of Cardiac Surgery, Onassis Cardiac Surgery Center, 176 74 Athens, Greece.
Journal of clinical medicine
|November 25, 2023
概括
胸内血管大动脉修复 (TEVAR) 是可行的选择患者与A型大动脉解剖 (TAAD) 不适合开放手术. 需要进一步的研究来确定其在TAAD治疗中的长期作用.
科学领域:
- 心血管外科心血管外科
- 血管内干预 血管内干预
- 大动脉疾病管理管理
背景情况:
- 开放式手术是A型大动脉解剖 (TAAD) 的黄金标准.
- 胸内血管大动脉修复 (TEVAR) 是针对高度精选的患者考虑的.
- 这项研究评估了TAAD患者的TEVAR结果,这些患者不适合进行开放式手术.
研究的目的:
- 评估TEVAR在TAAD患者中的可行性和结果.
- 评估不适合开放修复的个体的内血管治疗.
- 在这个队列中分析与TEVAR相关的生存率和并发症率.
主要方法:
- 对PubMed,Scopus和Cochrane数据库进行符合PRISMA的系统审查.
- 包括20项符合条件的研究,包括311名接受TAADTEVAR治疗的患者.
- 使用卡普兰-梅尔曲线分析的时间到事件数据.
主要成果:
- 平均年龄为60.7岁;75.48%是男性.
- 转换为开放性手术 (0.44%),技术故障 (0.22%) 和中风 (0.1%) 的低率.
- 一年,三年和五年生存率分别为87.15%,82.52%和82.31%.
结论:
- 对于那些无法接受开放手术的精心挑选的TAAD患者来说,TEVAR是一种可行的选择.
- 长期数据和克服技术挑战对于定义TEVAR的作用至关重要.
- 需要进一步的研究来确定TAAD修复中的内血管治疗.
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