更年期导致女性患心血管疾病的风险增加
Magdalena Sylwia Kamińska1, Daria Schneider-Matyka2, Kamila Rachubińska2
1Subdepartment of Long-Term Care and Palliative Medicine, Department of Social Medicine, Faculty of Health Sciences, Pomeranian Medical University in Szczecin, 48 Żołnierska St., 71-210 Szczecin, Poland.
Journal of clinical medicine
|November 25, 2023
概括
更年期会增加心血管疾病 (CVD) 的风险,特别是当代谢综合征 (MetS) 存在时. 这项研究评估了更年期.
科学领域:
- 心血管医学 心血管医学
- 内分泌学 在内分泌学.
- 妇女健康 妇女健康
背景情况:
- 更年期显著影响女性的心血管健康.
- 相关变化包括心血管风险概况的改变,代谢健康标志物和亚临床动脉样硬化.
- 了解更年期在心血管疾病 (CVD) 发展中的作用至关重要.
研究的目的:
- 评估更年期和心血管疾病风险因素之间的关联.
- 评估与更年期有关的心脏代谢疾病的亚临床标志物.
- 研究更年期,代谢综合征和心血管风险之间的相互作用.
主要方法:
- 对235名处于更年期不同阶段的妇女进行了横截面研究.
- 使用诊断调查,人体测量 (WC,BMI,WHtR),血压和生物化学分析 (脂质,葡萄糖,胰岛素,HbA1c).
- 使用ASCVD风险计算器,POL-SCORE和SCORE-2评估心血管风险.
主要成果:
- 大多数女性在不同评估尺度上表现出低心血管风险.
- 绝经时的年龄不是一个独立的风险因素,但更老的年龄和更长的绝经时间与心血管疾病风险增加相关.
- 代谢综合征 (MetS) 是心血管疾病的重要独立风险因素,其赔率比为13.812.
结论:
- 更年期是增加心血管疾病风险的诱导因素.
- 代谢综合征显著提高女性心血管疾病的风险.
- 早期识别和治疗代谢综合征对于更年期妇女的心血管健康至关重要.
相关概念视频
Menopause
171
Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...
171
Psychoneuroimmunology: Cardiovascular Disease
31
Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
A key area of focus in PNI is the relationship between stress and coronary...
31
Disorders of the Female Reproductive System
368
The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
368
Bone Disorders
3.5K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
3.5K
Hormonal Regulation of the Menstrual Cycle
403
The ovarian cycle regulates endometrial changes throughout a single menstrual cycle via the coordinated action of gonadotrophin-releasing hormone (GnRH) and gonadotrophins.
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH...
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH...
403
Increased pulse rate
667
Tachycardia is a condition marked by an abnormally fast or irregular heart rate, surpassing the typical resting rate. In adults, tachycardia is characterized by a pulse rate ranging from 100 to 180 beats per minute. The increased heart rate can result in inadequate blood flow to various body parts, ultimately diminishing the oxygen supply to organs and tissues.
Many factors can elevate the risk of developing tachycardia. These include advanced age, a family history of arrhythmias, and an...
Many factors can elevate the risk of developing tachycardia. These include advanced age, a family history of arrhythmias, and an...
667


