基于BACES严重程度的Mycobacterium avium复杂肺部疾病的自发文化转化率
Bo-Guen Kim1, Jin Young Yu2, Byung Woo Jhun3
1Division of Pulmonary Medicine and Allergy, Department of Internal Medicine, Hanyang University College of Medicine, Seoul 04763, Republic of Korea.
Journal of clinical medicine
|November 25, 2023
概括
疾病的严重程度会影响Mycobacterium avium复杂肺病 (MAC-PD) 患者的自发培养转化. 较低的BACES分数表明培养转换的可能性更高,这表明严重程度评估是预测结果的关键.
科学领域:
- 肺部病理学 肺部病理学
- 传染性疾病 传染性疾病
- 临床医学 临床医学
背景情况:
- 在Mycobacterium avium复杂肺病 (MAC-PD) 中预测自发培养转化 (SCC) 是一个挑战.
- 很少有临床因素可用于预测MAC-PD患者的SCC.
研究的目的:
- 评估SCC发病率是否根据MAC-PD患者的疾病严重程度而有所不同.
- 评估MAC-PD中BACES严重程度和SCC之间的关联.
主要方法:
- 使用BACES标准 (BMI,年龄,腔,ESR,性别) 对373名MAC-PD患者的回顾性分类.
- 基于BACES严重程度的SCC发病率和影响因素的评估在没有抗生素的警等待患者中.
主要成果:
- 41%的患者在没有抗生素的情况下获得了SCC.
- 在BACES程度较轻的患者 (48%轻度,37%中度,24%严重) 中观察到更高的SCC发病率.
- 与中度和重度BACES相比,轻度BACES患者的良好结局明显更常见.
结论:
- 较低的BACES严重程度与MAC-PD中自发培养转换的可能性更高有关.
- BACES标准可以帮助预测MAC-PD患者的治疗结果.
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