在接受左心室辅助器件植入的患者中营养风险评估和不良事件 - 使用医院信息系统进行回顾性队列研究
Irena Milaniak1, Lucyna Tomaszek1, Sylwia Wiśniowska-Śmiałek2
1Faculty of Medicine and Health Sciences, Andrzej Frycz Modrzewski Krakow University, 30-705 Kraków, Poland.
Journal of clinical medicine
|November 25, 2023
概括
在左心室辅助器械 (LVAD) 手术前,晚期心力衰竭患者经常出现营养不良. 营养状况不佳显著增加了术后并发症和死亡率的风险.
科学领域:
- 心脏病学 心脏病学
- 营养科学 营养科学
- 外科手术的结果
背景情况:
- 晚期心力衰竭影响了很大一部分患者,其中30-70%的人患有营养不良.
- 这些患者的营养不良与术后不良事件的风险增加有关.
- 左心室辅助装置 (LVAD) 植入是晚期心力衰竭的关键干预措施.
研究的目的:
- 在接受LVAD植入的患者中评估术前营养状况.
- 评估营养状况和术后不良事件之间的关系.
- 确定能预测不良结果的营养不良评估方法.
主要方法:
- 对120名26-74岁的患者进行了回顾性队列研究,这些患者被转诊进行LVAD手术.
- 使用营养风险评分2002 (NRS-2002),营养风险指数 (NRI),预后营养指数 (PNI) 和总淋巴细胞计数 (TLC) 评估术前营养状况.
- 评估术后不良事件,包括急性功能衰竭和死亡率.
主要成果:
- 中度至严重的营养不良普遍存在,由PNI (55.8%),NRI (43.3%),TLC (40.0%) 和NRS-2002 (20%) 确定.
- 低TLC (<1200细胞/m3) 与术后急性功能衰竭 (HR: 2.5) 和死亡 (HR: 2.1) 的更高风险相关.
- 通过NRI和PNI评估的营养不良与增加的住院死亡率有显著联系 (HR:分别为4.9和5.0).
结论:
- 术前营养不良是术后急性功能衰竭和LVAD患者死亡率的重要危险因素.
- 使用营养风险评估工具可以帮助患者选择,并指导早期营养支持.
- 在LVAD植入前优化营养状况可能会改善手术结果并降低死亡率.
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