相关实验视频

Updated: Jun 25, 2026

Highly Efficient Gene Disruption of Murine and Human Hematopoietic Progenitor Cells by CRISPR/Cas9
08:27

Highly Efficient Gene Disruption of Murine and Human Hematopoietic Progenitor Cells by CRISPR/Cas9

Published on: April 10, 2018

13.5K

基于CRISPR-Cas9的基因敲除扩展NK细胞中的免疫检查点

Tahereh Mohammadian Gol1, Miso Kim1, Ralph Sinn1

  • 1Department of General Pediatrics, Hematology and Oncology, University Children's Hospital Tübingen, 72076 Tübingen, Germany.

International journal of molecular sciences
|November 25, 2023
PubMed
概括

在自然杀手 (NK) 细胞中抑制免疫检查点的CRISPR-Cas9基因编辑并没有显著提高其杀死癌症的能力. 需要进一步的研究来增强NK细胞免疫疗法用于白血病治疗.

关键词:
A2AR A2AR A2AR A2AR A2AR A2AR A2这是CBLB的CBLB.在CD96 CD96 CD96 CD96 CD96 CD96 CD96这就是CRISPR-Cas9的特征.在NKG2A中,它是NKG2A.免疫检查点的检查点.自然杀手细胞是自然杀手细胞.

更多相关视频

Generation of Knock-out Primary and Expanded Human NK Cells Using Cas9 Ribonucleoproteins07:20

Generation of Knock-out Primary and Expanded Human NK Cells Using Cas9 Ribonucleoproteins

Published on: June 14, 2018

12.5K
Gene Knock-in by CRISPR/Cas9 and Cell Sorting in Macrophage and T Cell Lines11:32

Gene Knock-in by CRISPR/Cas9 and Cell Sorting in Macrophage and T Cell Lines

Published on: November 13, 2021

10.6K

相关概念视频

Cytotoxic T Cells-mediated Immune Response01:27

Cytotoxic T Cells-mediated Immune Response

Cytotoxic T cells are a vital component of the immune system. They have the remarkable ability to identify and target antigens on infected or abnormal cells. These antigens often originate from intracellular pathogens such as viruses or abnormal proteins cancer cells produce.
Immunological surveillance is the ability of immune cells to monitor and eliminate infected cells with intracellular pathogens, neoplastically transformed cells, and cells with non-self antigens. Cytotoxic T cells and NK...
CRISPR/Cas9 Genome Editing01:28

CRISPR/Cas9 Genome Editing

The CRISPR-Cas system serves as a bacterial defense mechanism against invading genetic elements such as viruses and plasmids, forming the foundation for its adaptation as a powerful genome-editing tool. Originally discovered in prokaryotes, this system has been repurposed to revolutionize genetic engineering across a wide range of organisms, including plants, animals, and humans. The core component, Cas9, is an endonuclease derived from Streptococcus pyogenes, capable of introducing...