介素变异与IgA脏病的发展和进展有关:候选基因关联研究和元分析

Ioanna Chronopoulou1, Maria Tziastoudi1, Georgios Pissas1

  • 1Departments of Nephrology, Faculty of Medicine, School of Health Sciences, University of Thessaly, 41334 Larissa, Greece.

概括

介质蛋白基因变异,特别是在IL1B中,与免疫球蛋白A神经病变 (IgAN) 的进展有关. 这项研究确定了与增加IgAN风险和进展相关的特定IL1B多态和单元型.