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甲状腺疾病和全身性红斑性狼
Lambros Athanassiou1, Ifigenia Kostoglou-Athanassiou2, Georgia Kaiafa3
1Department of Rheumatology, Asclepeion Hospital, Voula, 16673 Athens, Greece.
Medicina (Kaunas, Lithuania)
|November 25, 2023
概括
与对照组相比,全身性红斑狼 (SLE) 患者的甲状腺疾病和可检测的抗甲状腺抗体的发病率较高. 这表明在狼患者的一个子组中存在甲状腺疾病的倾向.
科学领域:
- 内分泌学 在内分泌学.
- 类风湿病学 类风湿病学
- 自免疫性疾病 自免疫性疾病
背景情况:
- 甲状腺疾病经常与自身免疫性疾病有关.
- 系统性红斑狼 (SLE) 是一种复杂的自身免疫性疾病,具有广泛的影响.
- SLE和自身免疫性甲状腺疾病之间的特定关系需要进一步研究.
研究的目的:
- 评估SLE和自身免疫性甲状腺疾病之间的关联.
- 在SLE患者中确定甲状腺功能障碍和抗甲状腺抗体的患病率.
主要方法:
- 在12个月内对45名SLE患者和45名年龄/性别匹配的对照进行了前性研究.
- 对临床甲状腺疾病 (甲状腺功能低下症,甲状腺功能过高症) 的评估.
- 测量抗甲状腺抗体,包括甲状腺过氧化酶 (TPOab) 和甲状腺球蛋白 (Tgab).
主要成果:
- 在SLE患者和对照人群中,原发性甲状腺功能低下症 (8.9%),亚临床性甲状腺功能低下症 (11.11%) 和甲状腺功能升高症 (2.22%) 的发病率较高.
- 在SLE患者中观察到11.11%的甲状腺病综合征.
- 与对照人群相比,SLE患者的TPOab (p < 0.05) 和Tgab (p < 0.05) 患病率明显较高.
结论:
- 临床甲状腺疾病在SLE患者中比在一般人群中更为普遍.
- 有相当数量的SLE患者表现出可检测的抗甲状腺抗体.
- 患有SLE的患者可能更容易患上甲状腺疾病,需要进行查.
关键词:
自免疫性甲状腺疾病.甲状腺功能过强症 甲状腺功能过强症甲状腺功能低下症 甲状腺功能低下症系统性红血性狼 (Systemic Lupus Erythematosus) 是一种全身性狼.铁血球蛋白抗体 铁血球蛋白抗体甲状腺过氧化酶抗体的抗体.更多相关视频
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