布拉西卡拉帕 (Brassica rapa) 水性提取物L对通过肠肌轴调节运动引起的疲劳的影响
Cheng Wang1,2, Hongkang Zhu1,2, Yuliang Cheng1,2
1School of Food Science and Technology, Jiangnan University, No.1800 Lihu Avenue, Wuxi 214122, China.
Nutrients
|November 25, 2023
概括
补充Brassica rapa L.可以通过改善肠道微生物群和能量代谢来帮助管理运动引起的疲劳. 它还可以减少炎症,并增强运动员的肠道完整性.
科学领域:
- 营养科学 营养科学
- 运动医学 运动医学
- 微生物学 微生物学
背景情况:
- 运动引起的疲劳与肠道微生物群和代谢变化有关.
- 布拉西卡拉帕 (Brassica rapa L.) 对生理反应具有潜在的调节作用.
研究的目的:
- 研究Brassica rapa L.对疲劳生物标志物,新陈代谢,炎症和肠道微生物群的影响.
- 探索其在运动引起的疲劳管理中的作用.
主要方法:
- 动物模型遭受慢性运动压力.
- 对疲劳生物标志物,能量代谢基因 (TCA循环,AMPK/PGC-1α/TFAM通路),炎症 (LPS,NF-κB),肠道完整性和肠道微生物群组成的分析.
- 细菌和生理标记之间的相关性分析.
主要成果:
- 布拉西卡拉帕L.表现出抗氧化活性和调节的疲劳反应.
- 通过AMPK/PGC-1α/TFAM通路影响肌肉TCA循环基因表达.
- 通过抑制LPS和NF-κB激活,减少炎症.
- 保持了肠道完整性和控制了格拉姆阴性细菌.
- 确定了特定肠道细菌与炎症/能量代谢之间的相关性.
结论:
- 布拉西卡拉帕 (Brassica rapa L.) 在通过肠道微生物群调节和代谢增强来管理运动引起的疲劳方面表现有前途.
- 在体育营养和医学的潜在治疗应用.
- 突出了饮食,肠道健康和运动表现之间的相互作用.
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