检查咖啡摄入量与患上刺激性肠综合征的风险之间的关联:系统性审查和元分析
Jasmine Yiling Lee1, Chun Yi Yau1, Caitlin Yuen Ling Loh1
1NUS Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore.
Nutrients
|November 25, 2023
概括
喝咖啡可能会降低患上刺激性肠综合征 (IBS) 的风险. 这项元分析发现,咖啡消费与成年人患IBS的可能性较低有关.
科学领域:
- 胃肠病学 胃肠病学
- 营养科学 营养科学
- 流行病学 流行病学
背景情况:
- 刺激性肠综合征 (IBS) 是一种常见的脑肠相互作用障碍,影响生活质量.
- 咖啡是一种流行的饮料,含有具有潜在健康影响的生物活性化合物.
- 现有关于咖啡对IBS风险的影响的研究提出了相互矛盾的发现.
研究的目的:
- 系统地审查和对现有研究进行元分析.
- 为了确定咖啡摄入量与发展IBS的风险之间的关联.
主要方法:
- 在PubMed,EMBASE和Cochrane图书馆进行了系统的文献搜索,直到2023年3月31日.
- 包括8项涉及432,022名参与者的研究.
- 几率比率 (ORs) 用固定效应模型计算和聚合.
主要成果:
- 与不喝咖啡的人相比,喝咖啡的人患IBS的可能性较低.
- 聚合的OR为0.84 (95% CI:0.80至0.84),表明一种保护性关联.
- 敏感性分析证实了这些发现的可靠性.
结论:
- 定期饮用咖啡似乎与患IBS的风险较低有关.
- 建议进一步进行高质量的前性队列研究,以确认发生IBS的发展.
相关概念视频
Irritable Bowel Syndrome I: Introduction
280
Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
280
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
165
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
165
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
335
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
335
Irritable Bowel Syndrome III: Medical and Nursing Management
212
Managing Irritable Bowel Syndrome (IBS) involves a multifaceted approach, including lifestyle modifications, dietary changes, and medication.
212
Drugs for Treatment of Constipation-Predominant IBS
179
Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
179
Chronic Bowel Disorders: Introduction
456
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
456


