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减肥用各种宏观营养素分布的替代餐饮计划对肠道微生物组和代谢参数的短期影响:试点研究

Seungmin Song^1,2, Jinyoung Shon^1,2, Woo-Ri Yang³

¹Graduate Program in System Health Science and Engineering, Ewha Womans University, Seoul 03760, Republic of Korea.

|November 25, 2023

概括

减肥饮食影响肠道微生物群,改变了Firmicutes/Bacteroidetes的比率. 富含蛋白质的替代性饮食增强了超重个体的肠道微生物多样性.

科学领域:

微生物学微生物学
营养科学营养科学
代谢健康代谢健康

背景情况:

肠道微生物组在代谢健康和肥胖中发挥着关键作用.
大量营养素的分布是减肥的关键因素,但其对肠道微生物群的影响尚不清楚.

研究的目的:

研究低卡路里餐替代计划中不同宏观营养素比例对肠道微生物群和代谢参数的影响.
为了比较均衡,高脂低碳水化合物和富含蛋白质饮食对肠道微生物组合和多样性的影响.

主要方法:

60名超重或肥胖的参与者接受了为期3周的低卡路里饮食替代干预.
测试了三种不同的宏观营养素比例:平衡 (60:15:30),高脂低碳水化合物 (35:20:55) 和蛋白质丰富 (40:25:35).
分析了肠道微生物群的组成,包括类繁多和多样性,以及代谢参数.

主要成果:

所有的饮食干预都导致了体重和BMI的减少.
在所有组中,Firmicutes/Bacteroidetes (F/B) 的比率都增加,特别是在均衡且富含蛋白质的饮食中.
富含蛋白质的饮食显著提高了类层面的α和β多样性.

结论:

短期减肥替代性饮食计划促进有益的肠道细菌,增加酸盐生产者和F/B比率.
与均衡和高脂饮食相比,富含蛋白质的饮食在改善肠道微生物多样性方面表现出更高的有效性.

关键词:

卡路里限制卡路里限制我们的肠道微生物组.宏观营养素的分布分布作为一餐的替代品.这是短期的饮食干预.

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