个性化与标准化维生素D补充剂对运动员25 (OH) D水平的影响
Chiara Tuma1,2, Arne Schick1, Nele Pommerening1
1Institute of Biochemistry/Center of Preventive Doping Research, German Sport University Cologne, 50933 Cologne, Germany.
Nutrients
|November 25, 2023
概括
个性化维生素D剂量有效地提高了运动员的25-OH-D水平超过40ng/mL,优于标准补充剂. 这种个性化的方法确保了体育表现的最佳维生素D状态.
科学领域:
- 运动医学 运动医学
- 营养生物化学 营养生物化学
- 内分泌学 在内分泌学.
背景情况:
- 维生素D对于运动员的健康和表现至关重要.
- 建议运动员的最佳25OH) D水平至少为40 ng/mL.
- 目前的补充策略可能无法根据运动员的个体需求量身定制.
研究的目的:
- 为了比较个性化的维生素D加载剂量公式与标准化剂量.
- 评估个性化补充剂在运动员中达到40 ng/mL的目标25...OH) D水平的有效性.
- 为了确定个性化的方法是否优于一套适合所有人的策略.
主要方法:
- 随机对照干预研究涉及90名体育运动员缺乏维生素D.
- 个性化加载剂量公式与标准化每日剂量 (2000 IU/天) 的比较.
- 在基线,目标实现和10周从干燥的血液斑点测量25...OH) D水平.
主要成果:
- 与标准化组 (32.5 ± 6.4 ng/mL) 相比,个性化剂量组在目标点 (p < 0.001) 达到显著更高的25(OH) D水平 (41.1 ± 10.9 ng/mL).
- 个性化的配方被证明是有效的,帮助运动员达到40 ng/mL 25(OH) D度.
- 这项研究是在德国的冬季进行的.
结论:
- 一个个性化的维生素D加载剂量配方对于运动员来说是有效的,以达到40ng/mL的25(OH) D度.
- 对运动员来说,个性化的维生素D补充策略比标准化的方法更有效.
- 这项研究支持量身定制的干预措施,以优化体育人群中维生素D状态.
更多相关视频
06:47Isolation of Mesenchymal Stem Cells from Human Alveolar Periosteum and Effects of Vitamin D on Osteogenic Activity of Periosteum-derived Cells
Published on: May 4, 2018
9.4K
07:40Impact of High-intensity Interval Exercise and Moderate-Intensity Continuous Exercise on the Cardiac Troponin T Level at an Early Stage of Training
Published on: October 10, 2019
7.3K
相关概念视频
01:23Role of Skin in Vitamin D Synthesis
5.2K
The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
5.2K
01:25Role of Vitamins in Maintaining Bone Health
3.3K
The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
3.3K
01:20Exercise and Cardiovascular Response
826
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
826
01:30Vitamins
732
Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced...
732
01:01Dosage Regimen: Fixed Dose
1.9K
Fixed-dose regimens are a common approach to administer drugs to achieve and maintain desired levels of the drug in the body. In this dosing strategy, a specific amount of medication is given at regular intervals, often multiple times a day, to ensure a consistent drug concentration in the bloodstream.
Fixed-dose regimens can be used for various routes of administration, including intravenous (IV) injections and oral medications. For IV administration, a predetermined amount of the drug is...
Fixed-dose regimens can be used for various routes of administration, including intravenous (IV) injections and oral medications. For IV administration, a predetermined amount of the drug is...
1.9K